Groundwater quality of Tehran city is considered in this study. Nine sampling stations were selected, and composite sampling campaign was performed in summer 2012. Groundwater sampled from northern stations appeared to have acceptable characteristics for agricultural and drinking uses. The southern station samples did not meet the required guidelines. Concentration of SO4 2−, Na+ and Cl− obey a sharp ascending trend southwards. Accordingly, the electrical conductivity of the last station at the very southern areas is more than fifteen times greater than that of the first northern station. Tehran city is located in a semi-arid climate and experiences long hot summers. High rates of evapo-transpiration within urban green spaces and agricultural lands facilitate the salinization phenomenon in root zones. As a result, excess irrigation water eases the consequent percolation into aquifers. Furthermore, saline water intrusion from salt marshes located down south of the city is an expected consequence of wells overpumping. Such case is especially remarkable in hot seasons when an increased urban water demand is observed. Remarkable sulfate concentrations in saline water are mainly justified by percolation of sulfate containing fertilizers which are broadly used by local farmers in an uncontrolled manner. Surface run-offs and municipal wastewater leakage may also trigger the salinization process.