The soil-water relationship was used to evaluate the efficacy of a novel remediation technology, the chemical-biological stabilization process, which focuses principally on soil fertility restoration in agricultural sites. This process was evaluated for the treatment of 150 m3 of bentonitic drilling muds from a closed sulfur mine which contained 70 % fines (<0.05mm), and which had been contaminated with very weathered hydrocarbons, containing 31% asphaltenes. This material was monitored for two and a half years, for in situ moisture content, field capacity, and soil water repellency. Additionally, critical soil moisture content for water drop penetration times of <5 and <60 s were monitored. Field capacity increased 46.6% with respect to initial values and a vigorous vegetative growth was established. Concurrently, water repellency values for molarity ethanol droplet and water drop penetration times were reduced from 5.1 M to 3.9 M and 106 h to 0.12 h, respectively. Soil in situ moisture content during the driest part of the year (20.3 % humidity) remained above critical values (15.1 % humidity and 19.5 % humidity) to avoid a water repellency of <5 s and <60 s, respectively, and water repellency was not observed in the field. Thus, complete mitigation of water repellency was achieved. These findings indicate that the soil-water relationship should be evaluated to achieve an integral soil remediation, and that water repellency as a remediation criterion should be complemented with determinations of critical moisture content and actual site information on soil in situ moisture content during the annual cycle.