The natural potential of Chrysanthemum indicum L for the clean-up of lead-contaminated soil was investigated under pot experiment. Maximum applied lead (at 50 mg/kg) caused significant reduction in the plant height (31.71%), root length (31.15%), dry biomass (32.71% and 41.25% for root and shoot, respectively), however, minimum applied lead (at 10 mg/kg) promoted the growth of plants to some extent, over the respective control pots. Lead concentration in the tissues followed the order as root>shoot>flower. The combinatorial treatment T¬16 [50 mg/kg Pb, 0.8 g/kg elemental sulphur and 6 g/kg vermicompost] caused maximum concentration of lead in root, shoot and flower up to the extent of 43.58, 22.45 and 9.62 mg/kg, respectively, leading to the maximum bioaccumulation factor (0.38). However, the combinatorial treatment T4 (sulphur and vermicompost) showed maximum translocation factor (0.63) and T12 (20 mg/kg lead, 0.8 g/kg elemental sulphur and 6 g/kg vermicompost) produced maximum remediation ratio (0.153). The combinatorial treatments under lead-contaminated (10-50 mg/kg) soils showed higher remediation efficiency indicating enhanced clean-up of the aforesaid soils through Chrysanthemum indicum L. Applied lead (>20 mg/kg) altered the chlorophyll-a, chlorophyll-b, and carotenoid contents of the plants. Hence, the authors conclude that a non-edible ornamental plant, Chrysanthemum indicum L, is preferred to be safely grown in moderately lead-contaminated soils along with application of elemental sulphur and vermicompost, which will boost the photosynthetic pigments of the plants, leading to enhanced clean-up of the lead-contaminated soil.